The Role of Oxytocin in the Second Stage of Labor

NARecruitingINTERVENTIONAL
Enrollment

400

Participants

Timeline

Start Date

July 1, 2022

Primary Completion Date

December 1, 2024

Study Completion Date

June 30, 2025

Conditions
Labor Complication
Interventions
DRUG

Continue Oxytocin

The administration and titration of oxytocin for labor augmentation is per a hospital based protocol. To summarize, oxytocin is initiated intravenously at 2 milliunits/minute and increased by 2 milliunits/minute every 20 minutes until an adequate contraction pattern is attained or a maximum of 40 millunits/minute has been achieved. This protocol for titration and administration will be applied in this study to the oxytocin group. The intravenous pumps on Labor and Delivery have automated functions for intravenous administration of oxytocin that is milliunit-based and the same routine pumps will be used in this study. The study bag will be administered per current oxytocin protocol. Since patients will already be on oxytocin at time of randomization, their current bag of oxytocin will be continued by the primary provider at a rate of their discretion.

OTHER

Discontinue Oxytocin

Patients will have their oxytocin discontinued in the second stage of labor. The patient will receive routine maintenance IV fluids per the discretion of the provider.

Trial Locations (1)

63110

RECRUITING

Barnes Jewish Hospital, St Louis

All Listed Sponsors
collaborator

University of Michigan

OTHER

lead

Washington University School of Medicine

OTHER