Chloroquine/ Hydroxychloroquine Prevention of Coronavirus Disease (COVID-19) in the Healthcare Setting

NACompletedINTERVENTIONAL
Enrollment

4,652

Participants

Timeline

Start Date

April 29, 2020

Primary Completion Date

March 22, 2022

Study Completion Date

March 22, 2022

Conditions
COVID19CoronavirusAcute Respiratory Illnesses
Interventions
DRUG

Chloroquine or Hydroxychloroquine

A loading dose of 10 mg base/ kg followed by 155 mg daily (250mg chloroquine phosphate salt or 200mg of or hydroxychloroquine sulphate) will be taken for 3 months

DRUG

Placebo

Placebo

Trial Locations (25)

10400

Faculty of Tropical Medicine, Mahidol University, Bangkok

20112

Bunda Thamrin Hospital, Medan

20231

Murni Teguh Memorial Hospital, Medan

55281

Sardjito Hospital, Yogyakarta

56700

B.P. Koirala Institute of Health Sciences, Dharān

60115

Airlangga University Hospital (UNAIR), Surabaya

60131

Husada Utama Hospital, Surabaya

74800

The Aga Khan University Hospital, Karachi

Unknown

Centre Hospitalier et Universitaire de Zone Abomey-Calavi, Abomey-Calavi

Hospital De Zone Allada, Allada

Fountain Healthcare Hospital, Eldoret

Mbagathi County Hospital, Nairobi

Zambart, Lusaka

BP 54378

University Hospital Center of Angre, Abidjan

BP 1174

University Hospital Center of Bouake, Bouaké

BP251

The Bamako Hospital of Dermatology, Bamako

BP3333

Hospital Of Mali, Bamako

LA9 7RG

University Hospitals Of Morecambe Bay NHS Foundation Trust, Kendal

DY1 2HQ

The Dudley Group NHS Foundation Trust, Dudley

B1 3RB

Birmingham & Solihull Mental Health NHS Trust, Birmingham

BN2 5BE

Brighton and Sussex University Hospitals NHS Trust, Brighton

CV2 2DX

University Hospitals Coventry and Warwickshire NHS Trust, Coventry

DN4 8QN

Rotherham, Doncaster And South Humber NHS Foundation Trust, Doncaster

W2 1NY

Imperial College Healthcare NHS Trust, London

OX3 9DU

Oxford University Hospital NHS Foundation Trust, Oxford

All Listed Sponsors
lead

University of Oxford

OTHER

NCT04303507 - Chloroquine/ Hydroxychloroquine Prevention of Coronavirus Disease (COVID-19) in the Healthcare Setting | Biotech Hunter | Biotech Hunter