NCT04302116View on ClinicalTrials.gov

Vigabatrin With High Dose Prednisolone Combination Therapy vs Vigabatrin Alone for Infantile Spasm

NARecruitingINTERVENTIONAL
Enrollment

250

Participants

Timeline

Start Date

May 18, 2020

Primary Completion Date

June 30, 2026

Study Completion Date

December 31, 2026

Conditions
Infantile SpasmWest Syndrome
Interventions
DRUG

Combination therapy with vigabatrin and prednisolone

High dose prednisolone (40 - 60 mg/day) for 1 month combined with vigabatrin treatment (50-150 mg/kg/day) twice daily for 4 months

DRUG

Vigabatrin Tablets

Vigabatrin (50-150 mg/kg/day) twice daily for 4 months

Trial Locations (1)

10400

RECRUITING

Queen Sirikit National Institute of Child Health, Ratchathewi

All Listed Sponsors
lead

Kullasate Sakpichaisakul

OTHER_GOV