Eflornithine (DFMO) and Etoposide for Relapsed/Refractory Neuroblastoma

PHASE2RecruitingINTERVENTIONAL
Enrollment

131

Participants

Timeline

Start Date

September 25, 2020

Primary Completion Date

October 1, 2028

Study Completion Date

October 1, 2033

Conditions
Neuroblastoma
Interventions
DRUG

Eflornithine

DFMO (difluoromethylornithine) will be given at a dose of 1000 mg/m2 BID on each day of study.

Trial Locations (29)

17033

RECRUITING

Penn State Milton S. Hershey Medical Center and Children's Hospital, Hershey

23507

RECRUITING

Children's Hospital of The King's Daughters, Norfolk

28204

RECRUITING

Levine Children's Hospital, Charlotte

29425

NOT_YET_RECRUITING

Medical University of South Carolina, Charleston

30912

RECRUITING

Augusta University Health, Augusta

32806

RECRUITING

Arnold Palmer Hospital for Children, Orlando

33614

RECRUITING

St. Joseph's Children's Hospital, Tampa

35201

RECRUITING

University of Alabama, Children's Alabama, Birmingham

40201

RECRUITING

University of Louisville, Louisville

44195

RECRUITING

Cleveland Clinic Children's, Cleveland

49503

RECRUITING

Helen DeVos Children's Hospital, Grand Rapids

53226

RECRUITING

Medical College of Wisconsin, Milwaukee

55404

RECRUITING

Children's Hospital and Clinics of Minnesota, Minneapolis

63104

RECRUITING

Cardinal Glennon Children's Hospital, St Louis

64108

RECRUITING

Children's Mercy Hospitals and Clinics, Kansas City

72202

RECRUITING

Arkansas Children's Hospital, Little Rock

75235

RECRUITING

Children's Medical Center Dallas, Dallas

78723

RECRUITING

Dell Children's Blood and Cancer Center, Austin

92123

RECRUITING

Rady Children's Hospital, San Diego

94609

RECRUITING

UCSF Benioff Children's Hospital Oakland-, Oakland

96813

RECRUITING

Kapiolani Medical Center for Women and Children, Honolulu

06106

RECRUITING

Connecticut Children's Hospital, Hartford

07601

RECRUITING

Hackensack University Medical Center, Hackensack

02901

RECRUITING

Hasbro Children's Hospital, Providence

Unknown

RECRUITING

CancerCare Manitoba, Winnipeg

RECRUITING

UHC Sainte-Justine, Montreal

RECRUITING

CHUQ, Québec

RECRUITING

CIUSSS de l'Estrie-CHUS, Sherbrooke

H4A 3J1

RECRUITING

Montreal Children's Hospital, Montreal

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

K C Pharmaceuticals Inc.

INDUSTRY

collaborator

Beat NB Cancer Foundation

OTHER

collaborator

Team Parker for Life

UNKNOWN

collaborator

USWM, LLC

UNKNOWN

lead

Giselle Sholler

OTHER