Cellular Pharmacology and Platelet Effects of Abacavir and Lamivudine Anabolites

CompletedOBSERVATIONAL
Enrollment

25

Participants

Timeline

Start Date

March 6, 2020

Primary Completion Date

December 17, 2021

Study Completion Date

December 17, 2021

Conditions
HIV-1-infection
Interventions
OTHER

Blood collection

Blood will be collected from participants at defined time points during the study to measure drug levels and assess platelet activity.

DRUG

Abacavir/lamivudine

Participants who are already taking abacavir/lamivudine as part of standard HIV care will continue taking their therapy.

DRUG

Tenofovir alafenamide/emtricitabine

Participants who are already taking tenofovir alafenamide/emtricitabine as part of standard HIV care will continue taking their therapy.

DRUG

Switch

Participants who are planning to switch from abacavir/lamivudine as part of standard HIV care will change therapy to per the discretion of their HIV provider.

Trial Locations (1)

80045

University of Colorado Hospital, Aurora

All Listed Sponsors
lead

University of Colorado, Denver

OTHER

NCT04301661 - Cellular Pharmacology and Platelet Effects of Abacavir and Lamivudine Anabolites | Biotech Hunter | Biotech Hunter