Identifying Novel Variants in the DPYD Gene in Patients of Non-Western Descent

UnknownOBSERVATIONAL
Enrollment

600

Participants

Timeline

Start Date

March 1, 2020

Primary Completion Date

March 1, 2022

Study Completion Date

August 1, 2022

Conditions
Neoplasms
Interventions
GENETIC

Sequencing of DPYD gene

The DPYD gene of non-Western patients will be sequenced to identify DPYD variants that are possibly associated with an increased risk of developing severe fluoropyrimidine-related toxicity.

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

The Netherlands Cancer Institute

OTHER

collaborator

Erasmus Medical Center

OTHER

collaborator

Haga Hospital

OTHER

collaborator

Medical Center Haaglanden

OTHER

lead

Leiden University Medical Center

OTHER