The Impact of Insomnia on Pain in HIV

CompletedOBSERVATIONAL
Enrollment

171

Participants

Timeline

Start Date

January 1, 2020

Primary Completion Date

July 31, 2025

Study Completion Date

July 31, 2025

Conditions
HIVInsomnia
Interventions
DIAGNOSTIC_TEST

Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5)sleep disorders-revised

Structured Clinical Interview For DSM-5 Sleep Disorders-Revised (SCISD-R) - is a semi structured interview for diagnosing sleep disorders according to Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5)

DIAGNOSTIC_TEST

Resmed ApneaLink Air device (Resmed, San Diego, CA).

Home Sleep Test (HST) will measure airflow (i.e., nasal pressure) using a nasal cannula and oxygen saturation to identify apnea and hypopnea and calculate an apnea hypopnea index (AHI; number of apnea and hypopnea per hour).

OTHER

Quantitative Sensory testing (QST)

All participants will undergo quantitative sensory testing for assessment of endogenous pain modulation using painful heat, mechanical, and cold stimuli in a laboratory session lasting approximately 1 hour.

DIAGNOSTIC_TEST

OraQuick Advance Rapid HIV 1/2 Swab test

Participants who have an HIV negative status will complete the OraQuick Advance Rapid HIV 1/2 Swab test to confirm negative status.

DIAGNOSTIC_TEST

Cluster of Differentiation 4 (CD4) and Viral load

Participants who have an HIV positive status will have blood tested for cluster of differentiation 4 (CD4) and Viral load to confirm positive status.

Trial Locations (1)

35294

UAB, Birmingham

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

University of Alabama at Birmingham

OTHER

NCT04298658 - The Impact of Insomnia on Pain in HIV | Biotech Hunter | Biotech Hunter