Role of Pharmacotherapy in Counteracting Weight Regain in Adolescents With Severe Obesity

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

August 4, 2021

Primary Completion Date

June 30, 2026

Study Completion Date

June 30, 2027

Conditions
Obesity
Interventions
DRUG

Phentermine-Topiramate

The study medication to be tested for this study is a combination of phentermine and topiramate.

DIETARY_SUPPLEMENT

Meal Replacement Therapy

The first six weeks of the study, subjects will receive meal replacement therapy in an effort to reduce their BMI by at least 5%.

OTHER

Placebo

A pill that looks like Phentermine-Topiramate but has no active medication.

Trial Locations (1)

55455

University of Minnesota, Minneapolis

All Listed Sponsors
lead

University of Minnesota

OTHER