A Safety, Pharmacokinetics and Efficacy Study of MAU868 for the Treatment of BK Viremia in Kidney Transplant Recipients

PHASE2CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

August 5, 2020

Primary Completion Date

February 10, 2022

Study Completion Date

February 10, 2022

Conditions
BK Virus Infection
Interventions
DRUG

MAU868

MAU868 is a human monoclonal antibody (IgG1) that binds the viral capsid protein, VP1, that is responsible for binding to the surface of host cells

OTHER

Placebo

250 mL D5W placebo IV to be labeled to match that of MAU868

Trial Locations (18)

10467

Montefiore Medical Center, The Bronx

15213

University of Pittsburgh Medical Center (UPMC), Pittsburgh

21205

The Johns Hopkins University, Baltimore

37232

Vanderbilt University Medical Center, Nashville

40506

University of Kentucky, Lexington

44106

University Hospitals Cleveland Medical Center, Cleveland

63130

Washington University, St Louis

75235

Renal Disease Research Institute, LLC, Dallas

75390

The University of Texas Southwester Medical Center, Dallas

77030

Houston Methodist Research Institute, Houston

90048

Cedars-Sinai Medical Center, Los Angeles

98195

University of Washington, Seattle

35294-0111

University of Alabama at Birmingham, Birmingham

06511

Yale University, New Haven

02241

Massachusetts General Hospital, Boston

M5G 2C4

University Health Network, Toronto

H1T 2M4

Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Est de-l'Île-de-Montréal, Montreal

H4A 3J1

The Research Institute of the McGill University Health Centre, Montreal

All Listed Sponsors
lead

Vera Therapeutics, Inc.

INDUSTRY

NCT04294472 - A Safety, Pharmacokinetics and Efficacy Study of MAU868 for the Treatment of BK Viremia in Kidney Transplant Recipients | Biotech Hunter | Biotech Hunter