Comparing Individual Therapies for Veterans With Depression, PTSD, and Panic Disorder

NACompletedINTERVENTIONAL
Enrollment

304

Participants

Timeline

Start Date

October 1, 2020

Primary Completion Date

January 1, 2025

Study Completion Date

March 31, 2025

Conditions
Major Depressive DisorderPosttraumatic Stress DisorderPanic Disorder and Agoraphobia
Interventions
BEHAVIORAL

Transdiagnostic Behavior Therapy

TBT was developed to address transdiagnostic avoidance via the use of four different types of exposure techniques (situational/in-vivo, physical/interoceptive, thought/imaginal, and \[positive\] emotional/behavioral activation). From the transdiagnostic avoidance perspective, the four exposure practices are matched to the type(s) of avoidance experienced by patients based upon their cluster of symptoms/disorders.

BEHAVIORAL

Cognitive Processing Therapy for PTSD

CPT is a well established evidence-based psychotherapy for PTSD. CPT focuses on teaching patients to evaluate and change the upsetting thoughts that they have had since their trauma.

BEHAVIORAL

Cognitive Behavioral Therapy for MDD

CBT for MDD is a well established evidence-based psychotherapy for depression. CBT for MDD focuses teaching patients how to change their behaviors and challenge their negative thoughts to improve their mood.

BEHAVIORAL

Cognitive Behavioral Therapy for Panic Disorder

CBT for Panic Disorder is a well established evidence-based psychotherapy. CBT for Panic Disorder focuses teaching patients how to change their behaviors through exposure practices and challenge their anxious thoughts to reduce their experience of panic attacks and avoidance.

Trial Locations (1)

29401-5703

Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston

All Listed Sponsors
lead

VA Office of Research and Development

FED

NCT04293341 - Comparing Individual Therapies for Veterans With Depression, PTSD, and Panic Disorder | Biotech Hunter | Biotech Hunter