Back-to-back Endoscopy Versus Single-pass Endoscopy and Chromoendoscopy in IBD Surveillance

NACompletedINTERVENTIONAL
Enrollment

563

Participants

Timeline

Start Date

March 13, 2020

Primary Completion Date

May 23, 2023

Study Completion Date

November 7, 2023

Conditions
Inflammatory Bowel DiseasesColorectal Neoplasms
Interventions
PROCEDURE

Back-to-back high-definition white light endoscopy

Using HD white light, the entire colon is examined for dysplasia and other abnormalities after the caecum is reached, with a second segmental inspection after the first examination in the same session.The colonoscope has a high-definition camera and processor. All images are displayed on a high definition monitor for optimal resolution.

PROCEDURE

single-pass high-definition white light endoscopy

Using HD white light, the entire colon is examined for dysplasia and other abnormalities after the caecum is reached. The colonoscope has a high-definition camera and processor. All images are displayed on a high definition monitor for optimal resolution.

PROCEDURE

chromoendoscopy

After introduction of the endoscope into the colon a dye (methylene blue or indigo carmine) will be sprayed through a catheter positioned into the biopsy channel. Per segment, the entire colon is dyed, inspected, and lesions are removed. Equipment is similar to the other two interventions.

Trial Locations (4)

6525GA

Radboudumc, Nijmegen

3584CX

Utrecht University Medical Center, Utrecht

1105 AZ

Amsterdam UMC, location AMC, Amsterdam

Unknown

Leiden University Medical Center, Leiden

All Listed Sponsors
collaborator

UMC Utrecht

OTHER

collaborator

Leiden University Medical Center

OTHER

collaborator

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

OTHER

lead

Radboud University Medical Center

OTHER

NCT04291976 - Back-to-back Endoscopy Versus Single-pass Endoscopy and Chromoendoscopy in IBD Surveillance | Biotech Hunter | Biotech Hunter