Preoperative Biliary Drainage in Patients With Operable Malignant Periampulary Tumors

NACompletedINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

August 31, 2015

Primary Completion Date

October 31, 2017

Study Completion Date

October 31, 2019

Conditions
Periampullary CancerBiliary ObstructionPreoperative Biliary Drainage
Interventions
PROCEDURE

Preoperative Biliary Drainage (PBD)

Endoscopic retrograde biliary drainage (ERBD) and stent placement was the first choice for PBD while ultrasound-guided percutaneous transhepatic biliary drainage (PTBD) was done if ERBD was not feasible. Biliary drainage was considered successful if the serum bilirubin level decreased by 50% or more within 2 weeks after the procedure. Patients with failed PBD were referred directly to surgery, while those with successful PBD were referred to surgery 4 to 6 weeks after first drainage procedure according to the latest guidelines

PROCEDURE

Surgery

The standard surgical procedure for operable tumors Whipple procedure with triple reconstruction, namely pancreatogastrostomy or pancreatojejunostomy,hepaticojejunostomy and gastrojejunostomy

All Listed Sponsors
lead

University of Alexandria

OTHER

NCT04289831 - Preoperative Biliary Drainage in Patients With Operable Malignant Periampulary Tumors | Biotech Hunter | Biotech Hunter