Change in Brain Perfusion During Induction of General Anesthesia

RecruitingOBSERVATIONAL
Enrollment

101

Participants

Timeline

Start Date

January 27, 2021

Primary Completion Date

January 31, 2024

Study Completion Date

January 31, 2024

Conditions
Interventional RadiologyOrthopedic Surgery
Interventions
OTHER

Continuous monitoring of arterial blood pressure

For all patients, mean arterial pressure (unit mmHg) will be collected over three distinct periods: 1) baseline or during pre-oxygenation at FiO2 of 21% in awake patients, 2) before orotracheal intubation, and 3) just after mechanical ventilation.

OTHER

Transcranial Doppler

"Measurement of cerebral blood flow velocity (CFV) with use of Transcranial Doppler ultrasonography.~For all patients, CFV (unit cm/s) will be collected over three distinct periods: 1) baseline or during pre-oxygenation at FiO2 of 21% in awake patients, 2) before orotracheal intubation, and 3) just after mechanical ventilation."

OTHER

Bispectral Index (BIS)

"Continuous measurement of burst suppression (BS; %) with use of Bispectral Index (BIS).~For all patients, BS will be collected over three distinct periods: 1) baseline or during pre-oxygenation at FiO2 of 21% in awake patients, 2) before orotracheal intubation, and 3) just after mechanical ventilation"

OTHER

Near-infrared spectroscopy

"Continuous measurement of cerebral oxygen saturation (SO2) with Near-infrared spectroscopy (NIRS).~For all patients, SO2 (%) will be collected over three distinct periods: 1) baseline or during pre-oxygenation at FiO2 of 21% in awake patients, 2) before orotracheal intubation, and 3) just after mechanical ventilation."

Trial Locations (1)

75010

RECRUITING

AP-HP, Lariboisière Hospital, Department of Anesthesiology and Intensive Care, Paris

All Listed Sponsors
collaborator

INSERM UMR-942, Paris, France

OTHER

collaborator

LMS Ecole polytechnique

UNKNOWN

collaborator

M3DISIM Inria Université Paris-Saclay

UNKNOWN

lead

Assistance Publique - Hôpitaux de Paris

OTHER