Physiological Changes Induced Through MEP Conditioning in People With SCI

NAActive, not recruitingINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

February 22, 2021

Primary Completion Date

November 30, 2025

Study Completion Date

November 30, 2025

Conditions
Spinal Cord InjuriesNeurological InjuryParalysisSpasticity, Muscle
Interventions
COMBINATION_PRODUCT

Operant Conditioning

This is a training intervention in which the brain-spinal cord-muscle pathways are strengthened in individuals with incomplete spinal cord injury. Transcranial magnetic stimulation (TMS), a type of brain stimulation, will be used to elicit a muscle response from the tibialis anterior (TA), the muscle that lifts your toes and foot.

COMBINATION_PRODUCT

Control Group

This is the control intervention, or the non-conditioning group. Transcranial magnetic stimulation (TMS), a type of brain stimulation, will be used to elicit a muscle response from the tibialis anterior (TA), the muscle that lifts your toes and foot.

Trial Locations (1)

29425

Medical University of South Carolina, Charleston

All Listed Sponsors
collaborator

National Institute of Neurological Disorders and Stroke (NINDS)

NIH

lead

Medical University of South Carolina

OTHER