Intensive Intraperitoneal Therapy in Advanced Ovarian Cancer

PHASE2RecruitingINTERVENTIONAL
Enrollment

55

Participants

Timeline

Start Date

September 15, 2020

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2030

Conditions
Ovarian CancerIntraperitoneal Chemotherapy
Interventions
DRUG

Intraperitoneal chemotherapy during surgery

During interval surgery the patient will undergo HIPEC (Cisplatin 100mg/m2, 1h 30 infusions with sodium thiosulfate renal protection). They will then receive postoperative IPC i.e intravenous and intraperitoneal administration (IV Paclitaxel, 135mg/m2 on D1, IP Carboplatin, AUC 6 on D1, and IP Paclitaxel, 60mg/m2 on D8) with at least 3 courses performed (up to 4-6 allowed).

Trial Locations (1)

34298

RECRUITING

Institut du Cancer de Montpellier - Val d'Aurelle, Montpellier

All Listed Sponsors
collaborator

Direction Générale de l'Offre de Soins

OTHER_GOV

lead

Institut du Cancer de Montpellier - Val d'Aurelle

OTHER