Assessment of Paravalvular Leak After TAVI by Hemodynamic Measurements and Cardiac MRI

NAActive, not recruitingINTERVENTIONAL
Enrollment

92

Participants

Timeline

Start Date

September 17, 2019

Primary Completion Date

November 27, 2021

Study Completion Date

October 28, 2026

Conditions
Transcatheter Aortic Valve ReplacementHemodynamic MonitoringAortic Valve InsufficiencyAortic Valve StenosisHeyde's SyndromeAcquired Von Willebrand Disease
Interventions
PROCEDURE

cardiac MRI

"Patients are studied on a clinical 1.5 Tesla scanner with cardiac radiofrequency receiver coil centered over the heart, and ECG monitoring. The following parameters are assessed:~Functional imaging: ECG-gated cine Steady-state free precession (SSFP) MRI images are obtained during repeated breath holds in long axis and short axis orientations covering the entire left ventricle. Global systolic and diastolic function are assessed, and left ventricular mass is calculated.~Flow imaging: ECG-gated 2D flow measurements are assessed above the prosthetic valve, and at the level of the pulmonary trunk."

Trial Locations (1)

6525 GA

Radboudumc, Nijmegen

All Listed Sponsors
lead

Radboud University Medical Center

OTHER