NCT04281667View on ClinicalTrials.gov

Mechanical Bowel Preparation and Oral Antibiotics Versus Mechanical Bowel Preparation Only Prior Rectal Surgery

PHASE4Active, not recruitingINTERVENTIONAL
Enrollment

604

Participants

Timeline

Start Date

March 18, 2020

Primary Completion Date

November 9, 2022

Study Completion Date

October 10, 2027

Conditions
Rectal AdenocarcinomaRectum NeoplasmRectum CarcinomaColorectal CancerColorectal NeoplasmsColorectal CarcinomaSurgical Site InfectionSurgery--Complications
Interventions
DRUG

Oral Antibiotics

Oral antibiotics (neomycin 1g and metronidazole 1g at 3pm and 11pm the day before surgery)

DRUG

Placebo

Oral placebos (placebo 1 and placebo 2 at 3pm and 11pm the day before surgery)

DRUG

Mechanical Bowel Preparation

Mechanical Bowel Preparation using 2L polyethylene glycol (Moviprep)

Trial Locations (3)

Unknown

Helsinki University Hospital, Helsinki

Tampere University Hospital, Tampere

Turku University Hospital, Turku

All Listed Sponsors
lead

Helsinki University Central Hospital

OTHER