Effect of Tumor Treating Fields (TTFields, 150 KHz) Concomitant with Chemotherapy As First Line Treatment of Unresectable Gastroesophageal Junction or Gastric Adenocarcinoma

NACompletedINTERVENTIONAL
Enrollment

28

Participants

Timeline

Start Date

December 19, 2019

Primary Completion Date

June 7, 2024

Study Completion Date

June 7, 2024

Conditions
Gastric CancerGastroEsophageal Cancer
Interventions
DEVICE

NovoTTF-100L(P)

Patients receive continuous TTFields treatment using the NovoTTF-100L(P) device. TTFields treatment will consist of wearing four electrically insulated electrode arrays on the abdomen. The treatment enables the patient to maintain regular daily routine.

DRUG

Oxaliplatin

Oxaliplatin 130 mg/m\^2 intravenous infusion will be administered once every 3 weeks

DRUG

Capecitabine

Capecitabine 1000mg/m\^2 taken by mouth, twice daily on day 1-14, 3 weeks per cycle

DRUG

Trastuzumab

Trastuzumab (HER-2 positive patients only) intravenous infusion will be administered once every 3 weeks on Day 1 of each cycle. First dose is 8mg/kg, followed by 6 mg/kg.

Trial Locations (1)

Unknown

Queen Mary Hospital, Hong Kong

All Listed Sponsors
collaborator

Zai Lab (Shanghai) Co., Ltd.

INDUSTRY

lead

NovoCure Ltd.

INDUSTRY

NCT04281576 - Effect of Tumor Treating Fields (TTFields, 150 KHz) Concomitant with Chemotherapy As First Line Treatment of Unresectable Gastroesophageal Junction or Gastric Adenocarcinoma | Biotech Hunter | Biotech Hunter