A Study to Assess the Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP, an Autoimmune Disorder That Affects the Peripheral Nerves)

PHASE2CompletedINTERVENTIONAL
Enrollment

322

Participants

Timeline

Start Date

April 15, 2020

Primary Completion Date

May 11, 2023

Study Completion Date

May 11, 2023

Conditions
Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Interventions
BIOLOGICAL

efgartigimod PH20 SC in stage B

Stage A: efgartigimod PH20 SC, Stage B: efgartigimod PH20 SC

OTHER

placebo in stage B

Stage A: N/A, stage B: placebo

Trial Locations (216)

1038

Investigator site 3710001, Riga

1090

Investigator site 0430005, Vienna

Investigator site 0320017, Brussels

Investigator site 0320019, Brussels

1105

Investigator site 0310010, Amsterdam

1113

Investigator site 3590008, Sofia

1121

Investigator site 0360017, Budapest

Investigator site 0360018, Kistarcsa

1200

Investigator site 0320022, Woluwe-Saint-Lambert

1431

Investigator site 3590009, Sofia

1680

Investigator site 3590005, Sofia

2100

Investigator site 0450001, Copenhagen

2650

Investigator site 0320016, Edegem

3000

Investigator site 0320009, Leuven

4000

Investigator site 0320024, Liège

4021

Investigator site 0430008, Linz

4600

Investigator site 9950020, Kutaisi

5000

Investigator site 0450003, Odense

5020

Investigator site 0430006, Salzburg

5800

Investigator site 3590007, Pleven

6020

Investigator site 0430007, Innsbruck

8036

Investigator site 0430009, Graz

8200

Investigator site 0450002, Aarhus

10001

Investigator site 0010168, New York

10021

Investigator site 0010191, New York

10032

Investigator site 0010074, New York

10117

Investigator site 0490018, Berlin

10126

Investigator site 0390042, Torino

11000

Investigator site 3810001, Belgrade

Investigator site 3810003, Belgrade

11772

Investigator site 0010075, Patchogue

14011

Investigator site 0340019, Córdoba

14471

Investigator site 0490019, Potsdam

15123

Investigator site 0010067, Pittsburgh

15213

Investigator site 0010047, Philadelphia

19104

Investigator site 0010007, Philadelphia

21000

Investigator site 3800013, Kyiv

21009

Investigator site 380009, Vinnytsia

22903

Investigator site 0010007, Charlottesville

23298

Investigator site 0010061, Richmond

24105

Investigator site 0490016, Kiel

27517

Investigator site 0010003, Chapel Hill

27710

Investigator site 0010077, Durham

28007

Investigator site 0340017, Madrid

28040

Investigator site 0340018, Madrid

32209

Investigator site 0010023, Jacksonville

32751

Investigator Site 0010068, Maitland

32806

Investigator site 0010050, Orlando

33076

Investigator site 0330013, Bordeaux

33136

Investigator site 0010059, Miami

33487

Investigator site 0010072, Boca Raton

33612

Investigator site 0010006, Tampa

37075

Investigator site 0490044, Bochum

40536

Investigator site 0010147, Lexington

41013

Investigator site 0340016, Seville

43024

Investigator site 380008, Lutsk

43210

Investigator site 0010064, Columbus

44093

Investigator site 0330022, Nantes

45147

Investigator site 0490045, Essen

48201

Investigator site 0010014, Detroit

48824

Investigator site 0010063, East Lansing

49033

Investigator site 0330034, Angers

49069

Investigator site 3800012, Dnipro

50937

Investigator site 0490013, Cologne

52242

Investigator site 0010011, Iowa City

52621

Investigator site 9720005, Ramat Gan

58100

Investigator site 9720006, Holon

61058

Investigator site 3800015, Kharkiv

63003

Investigator site 0330033, Clermont-Ferrand

65212

Investigator site 0010028, Columbia

66205

Investigator site 0010015, Fairway

67098

Investigator site 0330020, Strasbourg

69068

Investigator site 3800011, Zaporizhzhya

75013

Investigator site 0330035, Paris

76008

Investigator site 3800010, Ivano-Frankivsk

78229

Investigator site 0010009, San Antonio

78756

Investigator site 0010066, Austin

79044

Investigator site 3800014, Dnipro

80112

Investigator site 0010057, Centennial

80131

Investigator site 0390007, Napoli

85018

Investigator site 0010013, Phoenix

85028

Investigator site 0010055, Scottsdale

87042

Investigator site 0330024, Limoges

92011

Investigator Site 0010032, Carlsbad

92270

Investigator site 0010160, Rancho Mirage

92380

Investigator site 0330025, Garches

92868

Investigator site 0010004, Orange

93053

Investigator site 0490015, Regensburg

94109

Investigator site 0010071, San Francisco

94275

Investigator site 0330023, Le Kremlin-Bicêtre

98125

Investigator site 0390027, Messina

100053

Investigator site 0860033, Beijing

117186

Investigator site 0070016, Moscow

Investigator site 0070020, Moscow

194354

Investigator site 0070014, Saint Petersburg

200090

Investigator site 0860047, Shanghai

210001

Investigator site 0860043, Nanjing

300723

Investigator site 0400003, Timișoara

310003

Investigator site 0860035, Hanzhou

330088

Investigator site 0860044, Nanchang

344022

Investigator site 0070019, Rostov-on-Don

350001

Investigator site 0860038, Fuzhou

410008

Investigator site 0860041, Changsha

420021

Investigator site 0070017, Kazan'

420097

Investigator site 0070023, Kazan'

430032

Investigator site 0070021, Saransk

430040

Investigator site 0860029, Wuhan

430060

Investigator site 0860034, Wuhan

500299

Investigation site 0400002, Brasov

510120

Investigator site 0860050, Guanzhou

510515

Investigator site 0860032, Guanzhou

550000

Investigator site 0860045, Guiyang

710038

Investigator site 0860048, Xi'an

710075

Investigator site 0860037, Xi'an

712000

Investigator site 0860054, Xiangyang

900591

Investigator site 0400004, Constanța

2500012

Investigator site 0860031, Jinan

6423906

Investigator site 9720004, Tel Aviv

35233-2110

Investigator site 0010065, Birmingham

91767-2009

Investigator site 0010190, Pomona

06520

Investigator site 0010026, New Haven

33067-4640

Investigator site 0010144, Coral Springs

32174-3102

Investigator site 0010172, Ormond Beach

30912-3125

Investigator site 0010125, Augusta

55455-4800

Investigator site 0010052, Minneapolis

08550

Investigator site 0010070, New Brunswick

06511

Investigator site 0010069, New York

45267-0525

Investigator site 0010051, Cincinnati

77055-7421

Investigator site 0010026, Houston

05401

Investigator site 0010076, Burlington

Unknown

Investigator site 0860030, Changchun

Investigator site 0860036, Chengdu

Investigator site 0860046, Hangzhou

Investigator site 0860063, Jining

Investigator Site 0860040, Nanchang

Investigator site 0860051, Nanchang

Investigator site 0860043, Nanjing

Investigator site 0860028, Shanghai

Investigator site 0860052, Shanghai

Investigator Site 9950002, Tbilisi

Investigator Site 9950003, Tbilisi

Investigator Site 9950004, Tbilisi

Investigator site 0490017, Berlin

Investigator site 0490021, Göttingen

Investigator site 0490014, Hanover

Investigator site 0490020, Leipzig

Investigator site 0390022, Brescia

Investigator site 0390029, Florence

Investigator site 0390024, Genova

Investigator site 0390003, Milan

Investigator site 0390026, Milan

Investigator site 0390023, Pisa

Investigator site 0390008, Roma

Investigator site 0390028, Siena

Investigator site 0810002, Chiba

Investigator site 0810034, Chūōku

Investigator site 0810029, Kawaguchi

Investigator site 0810026, Kodaira

Investigator site 0810027, Mibu

Investigator site 0810032, Nagoya

Investigator site 0810007, Osaka

Investigator site 0810028, Sagamihara

Investigator site 0310011, Rotterdam

Investigator site 0480022, Warsaw

Investigator site 0070018, Perm

Investigator site 3810004, Kragujevac

Investigator site 0340038, Barcelona

Investigator site 8860014, Kaohsiung City

Investigator site 8860015, Taichung

Investigator site 8860013, Tainan City

Investigator site 8860011, Taipei

Investigator site 8860012, Taipei

Investigator site 8860016, Taipei

Investigator site 8860017, Taoyuan District

Investigator site 0900025, Bursa

Investigator site 0900023, Istanbul

Investigator site 0900021, Izmir

Investigator site 0900022, Samsun

Investigator site 0900024, Sarıçam

Investigator site 3800015, Vinnytsia

Investigator site 0440017, Glasgow

Investigator site 0440015, Inverness

Investigator site 0440026, London

Investigator site 0440016, Oxford

Investigator site 0440018, Sheffield

Investigator site 0440019, Stoke-on-Trent

Investigator site 0440028, Tooting

024000

Investigator site 0860049, Chifeng

030001

Investigator site 0860042, Taiyuan

500-03

Investigator site 4200010, Hradec Králové

06202

Investigator site 0330021, Nice

0112

Investigator site 9950005, Tbilisi

113-8582

Investigator site 0810035, Bunkyō City

183-0042

Investigator site 0810030, Fuchū

812-8582

Investigator site 0810031, Fukuoka

901-214

Investigator site 0810065, Ginowan

041-0821

Investigator site 0810066, Hakodate

730-0011

Investigator site 0810058, Hiroshima

2016-0015

Investigator site 0810062, Kawasaki

616-8255

Investigator site 0810061, Kyoto

565-0871

Investigator site 0810003, Osaka

Investigator site 0810063, Suita

0608638

Investigator site 0810033, Sapporo

160-8582

Investigator site 0810037, Shinjuku-Ku

173-8606

Investigator site 0810036, tabashi City

770-0042

Investigator site 0810064, Tokushima

236-0004

Investigator site 0810060, Yokohama

15-402

Investigator site 0480019, Bialystok

40-650

Investigator site 0480023, Katowice

30-539

Investigator site 0480017, Krakow

31-202

Investigator site 0480024, Krakow

90-324

Investigator site 0480020, Lodz

20-090

Investigator site 0480018, Lublin

011302

Investigator site 0400001, Bucharest

03010

Investigator site 0340020, Alicante

08041

Investigator site 0340021, Badalona

Sponsors

Lead Sponsor

All Listed Sponsors
lead

argenx

INDUSTRY