Does Acoustic Stimulation During Sleep Boost Slow Wave Sleep and Memory Performance?

NACompletedINTERVENTIONAL
Enrollment

47

Participants

Timeline

Start Date

October 20, 2019

Primary Completion Date

July 20, 2023

Study Completion Date

July 20, 2023

Conditions
HealthyMild Cognitive ImpairmentAlzheimer Disease
Interventions
OTHER

Closed loop acoustic stimulation

The intervention consists of three consecutive nights of closed loop acoustic stimulation during slow wave sleep. An established closed-loop algorithm is utilized that detects slow oscillations in the electroencephalogram and is programmed to present short tones (50 ms) into their up-states. Tones will be presented via a headband with integrated speakers. The procedure does not wake participants

OTHER

Sham acoustic stimulation

Sham acoustic stimulation: participants wear the headband but no stimuli are delivered during slow wave sleep. This ensures that in both the control and the intervention group the conscious experiences are the same.

Trial Locations (1)

3000 60

University Hospital of Old Age Psychiatry and Psychotherapy, Bern

All Listed Sponsors
lead

University of Bern

OTHER

NCT04277104 - Does Acoustic Stimulation During Sleep Boost Slow Wave Sleep and Memory Performance? | Biotech Hunter | Biotech Hunter