NCT04274998View on ClinicalTrials.gov

Neuroinflammation Imaging in AD

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

March 3, 2020

Primary Completion Date

March 1, 2027

Study Completion Date

March 1, 2027

Conditions
Alzheimer DiseaseHealthy Volunteer
Interventions
DRUG

[18F]NOS

Main Study: PET/CT imaging will be used to evaluate neuroinflammation in the brain using the investigational radiotracer \[18F\]NOS.

DRUG

[11C]PBR28

Sub-Study: Additional PET/CT imaging will be used to evaluate neuroinflammation in the brain for subjects with specific genetic polymorphism using the investigational radiotracer \[11C\]PBR28 in comparison to \[18F\]NOS.

Trial Locations (1)

19104

RECRUITING

University of Pennsylvania, Philadelphia

All Listed Sponsors
lead

University of Pennsylvania

OTHER