The Influence of Two Different CO2 Absorbers on Sevoflurane Consumption During Anaesthesia

CompletedOBSERVATIONAL
Enrollment

38

Participants

Timeline

Start Date

February 12, 2020

Primary Completion Date

May 29, 2020

Study Completion Date

May 29, 2020

Conditions
Anesthesia
Interventions
OTHER

Comparing two CO2 absorbers in the ventilator circuit

"General anaesthesia will be induced with a standardised regimen (propofol 0.8-2.5 mg·kg-1, sufentanil 0.2 - 0.5 µg·kg-1 and rocuronium 0.5 - 1 mg·kg-1). After tracheal intubation, anaesthesia will be maintained with sevoflurane targeted at 1 MAC end tidal concentration (corrected for age using the formula by Mapleson) in 40% O2. Different ventilator settings will be compared for 30 minutes (in randomised order):~I. Sodalime, FGF 2.0 L min-1. II. Amsorb Plus®, FGF 2.0 L min-1. III. Soda lime, FGF, 0.5 L min-1. IV. Amsorb Plus®, FGF 0.5 L min-1. FGF=fresh gas flow."

Trial Locations (1)

1105 AZ

Amsterdam UMC, location AMC, Amsterdam

All Listed Sponsors
lead

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

OTHER

NCT04271462 - The Influence of Two Different CO2 Absorbers on Sevoflurane Consumption During Anaesthesia | Biotech Hunter | Biotech Hunter