NCT04265742 - Microbiota and Bone Fragility:Study of the Relation Between Gut Microbiota and Bone Microarchitecture | Biotech Hunter

Enrollment

440

Participants

Timeline

Start Date

February 8, 2019

Primary Completion Date

February 4, 2022

Study Completion Date

February 4, 2022

Conditions

Bone Loss, Age-related

Interventions

RADIATION

bone densitometry

Bone Mineral Density (BMD), body composition, vertebral fractures

RADIATION

High resolution peripheral QCT

High resolution peripheral QCT (HR-pQCT): bone microarchitecture and bone strength

DIAGNOSTIC_TEST

Collection of biological samples

Peripheral blood and urine samples to assess bone turnover markers and cytokines; and faeces to assess gut microbiota composition

OTHER

questionnaires

Epidemiologic and nutritional questionnaire and physical activity scale

OTHER

clinical tests

physical performance tests and grip strenght measurement

Trial Locations (1)

Hopital E. Herriot, Lyon

All Listed Sponsors

collaborator

Merck Sharp & Dohme LLC

INDUSTRY

lead

Institut National de la Santé Et de la Recherche Médicale, France

OTHER_GOV