458
Participants
Start Date
August 31, 2020
Primary Completion Date
June 30, 2026
Study Completion Date
March 31, 2027
Carotid artery stenting
The type of stent should be one commonly used for ICA stenting. Balloon angioplasty before and/or after stent placement will be allowed as required. Stenting should be performed after intracranial thrombectomy unless specific technical circumstances suggest that access to the intracranial circulation requires anterograde stenting. Embolic protection devices should not be used routinely during ICA stent placement.
Antiplatelet Agents
The following antiplatelet regimen should be used: For patients having received IV thrombolysis, immediate post-procedural oral or intrarectal single antiplatelet agents, (Aspirin 325mg PO or 650mg PR). A second agent (usually Clopidogrel 300mg PO) is added after follow-up brain imaging at 12-24 hours confirms absence of significant ICH. For patients having not been treated with IV thrombolysis, dual antiplatelet therapy (Aspirin 325mg PO or 650mg PR and Clopidogrel 300-600mg PO) is given immediately post-procedure. Routine use of GPIIb/IIIa inhibitors, periprocedural IV Heparin is discouraged.
RECRUITING
Centre Hospitalier de l'Université de Montréal, Montreal
McGill University
OTHER
Laval University
OTHER
Queen's University
OTHER
University of Ottawa
OTHER
McMaster University
OTHER
University of Calgary
OTHER
University of British Columbia
OTHER
Dalhousie University
OTHER
Health Sciences North Research Institute
OTHER
University of Toronto
OTHER
University of Alberta
OTHER
Canadian Stroke Consortium (CSC)
OTHER
Centre hospitalier de l'Université de Montréal (CHUM)
OTHER