59
Participants
Start Date
February 4, 2020
Primary Completion Date
October 6, 2022
Study Completion Date
February 22, 2023
Dexmedetomidine Hydrochloride [Dexdor]
Initial dosis of dexmedetomidine 1 mcg/kg IBW iv will be administered within 10 minutes before general anesthesia induction. Following intubation infusion of 1 mcg/kg IBW / h will be initiated and continued until the end of operation.
Remifentanil [Ultiva]
Remifentanil TCI Minto Model will be used during induction in dosis 6 ng/ml and intraoperatively appropriately to maintain hemodynamical stability.
Ketamine [Ketalar]
Ketamine 0,5mg/kg IBW iv will be administered during induction of general anesthesia.
Lidocaine [Xylocaine 2%]
Initial dosis of lidocaine 1,5 mg/kg IBW iv will be administered within 10 minutes before general anesthesia induction. Following intubation infusion of 3 mg/kg IBW / h will be initiated and continued until the end of operation.
Magnesium Sulphate [Inj. Magnesii Sulfurici Polpharma]
Magnesium Sulphate will be administered in dosis 50 mg/kg IBW iv intraoperatively.
Fentanyl [Fentanyl WZF]
Rescue dosis of 100 mcg iv will be administered if hypertension \> 140/90 mmHg or tachycardia \> 120min occurs. If necessary rescue dosis may be repeated.
Szpital Kliniczny Dzieciatka Jezus, Warsaw
Medical University of Warsaw
OTHER