Investigation of Relationship Between Vascular Functions, Exercise Capacity, and Respiratory Functions in CF

CompletedOBSERVATIONAL
Enrollment

60

Participants

Timeline

Start Date

April 11, 2022

Primary Completion Date

December 8, 2022

Study Completion Date

May 2, 2023

Conditions
Cystic Fibrosis
Interventions
OTHER

Maximal exercise test

The maximal exercise test will be performed on an electronically braked bicycle ergometer.

OTHER

Endothelial dysfunction assessment

Endothelial dysfunction will be determined by blood samples. Blood samples will be collected and analyzed for the responses of ICAM-1, VCAM-1, E-Selectin, VEGF, ET-1.

OTHER

Arterial stiffness assessment

Arterial stiffness, oscillometric pulse wave velocity (PWV) and augmentation index will be evaluated by recorded brachial pulse waves with automatically with the oscillometric device.

Trial Locations (1)

Unknown

Hacettepe University, Faculty of Physical Therapy and Rehabilitation, Ankara

All Listed Sponsors
lead

Hacettepe University

OTHER