Buckberg vs Del Nido in Isolated Aortic Valve Replacement

PHASE4CompletedINTERVENTIONAL
Enrollment

286

Participants

Timeline

Start Date

July 16, 2019

Primary Completion Date

August 24, 2023

Study Completion Date

August 24, 2023

Conditions
Cardiac Surgical Procedures
Interventions
DRUG

Del Nido

Del Nido cardioplegic solution administered in a single dose at 15-20mg/Kg with a maximum dose of 1L of solution, administered antegrade or retrograde. In those patients in wich the crossclamping time exceed 90 to 120 minutes a manteinance dose of 500ml will be administered.

DRUG

Buckberg

Buckberg cardioplegical solution administered antegrade and/or retrograde at 1-2ml/Kg for cardiac arrest induction. Arrest manteinance with antegrade and/or retrograde administration at 1-2ml/Kg every 15 to 20 minutes. Reperfusion dose with antegrade or retrograde administration at 15-20 ml/Kg before removing the aortic crossclamp.

Trial Locations (2)

08916

Hospital Germans Trias i Pujol, Badalona

08025

Hospital de la Santa Creu i Sant Pau, Barcelona

All Listed Sponsors
lead

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

OTHER

NCT04259515 - Buckberg vs Del Nido in Isolated Aortic Valve Replacement | Biotech Hunter | Biotech Hunter