NCT04255160View on ClinicalTrials.gov

Impact of Estradiol on Endothelial Function in Peri-Menopausal Women

PHASE4RecruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

October 1, 2020

Primary Completion Date

April 1, 2025

Study Completion Date

September 30, 2025

Conditions
PerimenopauseVasodilationEstrogen
Interventions
DRUG

Estradiol (mylan or vivelle dot patch)

Transdermal estradiol (0.1mg/day patch) will be used by women for 7 days. Administration of the patch will follow the package guidelines to change the patch after 3-4 days of use.

OTHER

Placebo

A placebo patch that is visually similar to the estradiol patch will be used for the group not receiving estradiol.

Trial Locations (1)

19716

RECRUITING

University of Delaware, Newark

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

University of Delaware

OTHER