RAMPS VS SRPS for Pancreatic Body and Tail Adenocarcinoma

NANot yet recruitingINTERVENTIONAL
Enrollment

224

Participants

Timeline

Start Date

February 15, 2020

Primary Completion Date

February 28, 2022

Study Completion Date

February 28, 2027

Conditions
Radical Antegrade Modular Pancreatosplenectomy
Interventions
PROCEDURE

Radical antegrade modular pancreatosplenectomy

"Radical antegrade modular pancreatosplenectomy (RAMPS) includes the following aspects. Firstly, the surgical approach is antegrade, which means from the right to the left, the pancreatic neck will be transected at first and the spleen will be seperated at last. Secondly, lymph nodes dissection includes not only the regional lymph nodes(No.10,11,18 lymph nodes), but also N1 station lymph nodes (N1: 6, 8a, 8p, 12a2/b2/p2, 13a/b, 14b/c/d, 14v, 17a/b), No.7, 9 lymph nodes, the lymph nodes anterior and left of superior mesenteric artery, as well as the peripheral nerve of celiac trunk. Thirdly, the transection platform is in the pancreatic neck, which is mandatory. At last, left prerenal fascia will be resected. When the tumor abuts or infiltrates the left adrenal gland, left adrenalectomy will be performed, which is also called posterior approach RAMPS. While in normal cases, left adrenal gland will be preserved."

PROCEDURE

Standard retrograde pancreatosplenectomy

"Standard retrograde pancreatosplenectomy(SRPS) includes several aspects. Firstly, the surgical approach is retrograde, which means from the left to the right, spleen will be seperated at first and the pancreas will be transected later on. Secondly, only the regional lymph nodes will be dissected, which include No.10, No.11, No.18 lymph nodes, and No.9 lymph nodes should be dissected only when the lesion is in pancreatic neck. Thirdly, the transection platform is in the left side of the lesion, but transection at pancreatic neck is not mandatory. At last, the surgical plane is anterior to the left renal fascia, prerenal fascia will be preserved."

Trial Locations (1)

200025

Ruijin Hospital affiliated to Shanghai Jiaotong University School of Medicine, Shanghai

All Listed Sponsors
lead

Ruijin Hospital

OTHER

NCT04253847 - RAMPS VS SRPS for Pancreatic Body and Tail Adenocarcinoma | Biotech Hunter | Biotech Hunter