Stem Cell Transplant From Donors After Alpha Beta Cell Depletion in Children and Young Adults

NARecruitingINTERVENTIONAL
Enrollment

204

Participants

Timeline

Start Date

February 1, 2020

Primary Completion Date

December 31, 2028

Study Completion Date

December 31, 2030

Conditions
Hematologic Diseases
Interventions
BIOLOGICAL

Allogeneic Stem Cell Transplant

The allogeneic stem cell transplant involves transferring the stem cells from a healthy person (donor) to the participant via infusion.

DEVICE

CliniMACS TCR α/β Reagent Kit and CliniMACS CD19

The CliniMACS™system can be used to selectively enrich or reduce specific cell populations based on the magnetic cell selection (MACS) technology developed by Miltenyi Biotec. Cell mixtures can be separated in a magnetic field using one or more immunomagnetic- labeled antibodies specific for the cell types of interest (e.g.TCR αβ+ T cells and CD19+ B cells from HPC(A) products).

Trial Locations (1)

94306

RECRUITING

Lucile Packard Children's Hospital, Palo Alto

All Listed Sponsors
lead

Alice Bertaina

OTHER