NCT04247646View on ClinicalTrials.gov

SLeep and OPioid UsE in Patients Undergoing Total Knee Arthroplasty

NAActive, not recruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

October 1, 2020

Primary Completion Date

March 1, 2025

Study Completion Date

December 31, 2028

Conditions
Opioid UsePain, PostoperativeSleepDelirium
Interventions
DIETARY_SUPPLEMENT

Melatonin

Participants will take sublingual melatonin (or placebo) nightly for 29 doses after undergoing total knee replacement surgery.

DIETARY_SUPPLEMENT

Placebo

Participants will take sublingual melatonin (or placebo) nightly for 29 doses after undergoing total knee replacement surgery.

Trial Locations (1)

92037-0001

Scripps Green Hospital, La Jolla

All Listed Sponsors
lead

Scripps Health

OTHER