NCT04242420 - Connexin Genotypes in Cystic Fibrosis | Biotech Hunter

Enrollment

300

Participants

Timeline

Start Date

April 30, 2002

Primary Completion Date

December 31, 2023

Study Completion Date

December 31, 2024

Conditions

Cystic FibrosisInflammation

Interventions

DIAGNOSTIC_TEST

Genotyping

Genotyping for single nucleotide polymorphisms for Connexin 37\&43, Mannose binding lectin (MBL) and transforming growth factor beta (TGF beta) genotypes

DIAGNOSTIC_TEST

Lung function

Spirometry,

DIAGNOSTIC_TEST

Microbiology

Bacterial culture from Sputum or swab

DIAGNOSTIC_TEST

Blood sample

Interleukin-8 assay (via chemiluminescence) blood cell count

DIAGNOSTIC_TEST

Induced Sputum

Interleukin-8 assay (via chemiluminescence) blood cell count

Trial Locations (3)

53113

RECRUITING

University Hospital, Bonn

60590

RECRUITING

University Hospital, Frankfurt

Unknown

RECRUITING

University Hospital, Amsterdam