NCT04237493 - Dosage Reduction and Acute Glycemic Complications in People With Type 2 Diabetes Who Fast During Ramadan | Biotech Hunter

Enrollment

687

Participants

Timeline

Start Date

February 14, 2017

Primary Completion Date

July 24, 2017

Study Completion Date

July 24, 2017

Conditions

Diabetes Mellitus, Type 2

Interventions

DRUG

Metformin and Glimepiride (Low Dosage)

"* Metformin (PO; 850 mg; BID \[with Ifṭār and with Suḥūr\])~* Glimepiride (PO; 1.5 or 3 mg \[75% of the pre-Ramadan dose\]; OD \[with Ifṭār\])"

DRUG

Metformin and Vildagliptin (Low Dosage)

"* Metformin (PO; 850 mg; BID \[with Ifṭār and with Suḥūr\])~* Vildagliptin (PO; 50 mg; OD \[with Ifṭār\])"

DRUG

Metformin and Insulin Glargine U100 (Low Dosage)

"* Metformin (PO; 850 mg; BID \[with Ifṭār and with Suḥūr\])~* Insulin Glargine U100 (SC; 9-33 units \[75% of the pre-Ramadan dose\]; OD \[at 10 P.M.\])"

DRUG

Metformin, Insulin Glargine U100, and Human Regular Insulin (Low Dosage)

"* Metformin (PO; 850 mg; BID \[with Ifṭār and with Suḥūr\])~* Insulin Glargine U100 (SC; 6-39 units (75% of the pre-Ramadan dose); OD \[at 10 P.M.\])~* Human Regular Insulin (SC; 15-33 units before Ifṭār and 6-18 units before Suḥūr \[75% of the pre-Ramadan doses\])"

DRUG

Metformin and Glimepiride (Regular Dosage)

"* Metformin (PO; 850 mg; BID \[with Ifṭār and with Suḥūr\])~* Glimepiride (PO; 2 or 4 mg \[100% of the pre-Ramadan dose\]; OD \[with Ifṭār\])"

DRUG

Metformin and Vildagliptin (Regular Dosage)

"* Metformin (PO; 850 mg; BID \[with Ifṭār and with Suḥūr\])~* Vildagliptin (PO; 50 mg; BID \[with Ifṭār and with Suḥūr\]\])"

DRUG

Metformin and Insulin Glargine U100 (Regular Dosage)

"* Metformin (PO; 850 mg; BID \[with Ifṭār and with Suḥūr\])~* Insulin Glargine U100 (SC; 11-44 units \[100% of the pre-Ramadan dose\]; OD \[at 10 P.M.\])"

DRUG

Metformin, Insulin Glargine U100, and Human Regular Insulin (Regular Dosage)

"* Metformin (PO; 850 mg; BID \[with Ifṭār and with Suḥūr\])~* Insulin Glargine U100 (SC; 8-52 units (100% of the pre-Ramadan dose); OD \[at 10 P.M.\])~* Human Regular Insulin (SC; 12-40 units before Ifṭār and 7-28 units before Suḥūr \[100% of the pre-Ramadan doses\])"

Trial Locations (1)

11942

Jordan University Hospital, Amman

All Listed Sponsors

lead

University of Jordan

OTHER