Nutritional Transitions to More Plant Proteins and Less Animal Proteins: Understanding the Induced Metabolic Reorientations and Searching for Their Biomarkers (ProVegOmics)

NACompletedINTERVENTIONAL
Enrollment

53

Participants

Timeline

Start Date

August 27, 2020

Primary Completion Date

August 5, 2022

Study Completion Date

August 5, 2022

Conditions
Metabolic SyndromeHypertriglyceridemiaFasting Blood Sugar Above NormalLower Than Standard HDL-cholesterol LevelSlightly Elevated Blood Pressure
Interventions
BEHAVIORAL

Diets with either predominantly animal protein sources.

20 men or postmenopausal women will follow for 4 weeks a controlled diet with a protein fraction constituted mainly from animal sources. At the end of the intervention period, a post-prandial exploration will be conducted with the administration of a high-fat, high-sugar meal and subsequent blood and urine sampling.

BEHAVIORAL

Diets with predominantly plant protein sources

20 men or postmenopausal women will follow for 4 weeks a controlled diet with a protein fraction constituted mainly from vegetal sources. At the end of the intervention period, a post-prandial exploration will be conducted with the administration of a high-fat, high-sugar meal and subsequent blood and urine sampling.

Trial Locations (1)

63000

CHU de Clermont-Ferrand, Clermont-Ferrand

All Listed Sponsors
collaborator

UMR 1019, Unité de Nutrition Humaine, INRA, Centre Auvergne-Rhône Alpes

UNKNOWN

collaborator

UMR 0914, Physiologie de la Nutrition et du Comportement Alimentaire, AgroParistech (adresse si besoin: 16 rue Claude Bernard, 75231 Paris Cedex 05).

UNKNOWN

lead

University Hospital, Clermont-Ferrand

OTHER

NCT04236518 - Nutritional Transitions to More Plant Proteins and Less Animal Proteins: Understanding the Induced Metabolic Reorientations and Searching for Their Biomarkers (ProVegOmics) | Biotech Hunter | Biotech Hunter