115
Participants
Start Date
November 27, 2017
Primary Completion Date
October 15, 2018
Study Completion Date
January 3, 2019
Plinabulin
Plinabulin (BPI-2358) is a synthetic, low molecular weight, new chemical entity that belongs to the diketopiperazine class of compounds. Plinabulin is intended for intravenous (IV) infusion and is diluted in D5W and administered for 30 minutes (± 5 minutes).
Pegfilgrastim
Pegfilgrastim is a long-acting granulocyte colony-stimulating factor that stimulates the growth of neutrophils, to reduce the incidence of fever and infection in patients with certain types of cancer who are receiving chemotherapy that affects the bone marrow.
Docetaxel, doxorubicin, and cyclophosphamide (TAC)
Docetaxel is a type of chemotherapy medicine called an taxane. Doxorubicin is a type of chemotherapy medicine called an anthracycline. Cyclophosphamide is a type of chemotherapy medicine called an alkylating agent.
Kirovograd Regional Oncological Center, Kropyvnytskyi
Dnipropetrovsk City Multifunctional Hospital #4 Oncology Department, Dnipro
Public Institution Kryvyi Rih Oncology Center, Krivoy Bereg
"V.T. Zaycev Institute of General and Urgent Surgery NAMS of Ukraine Dept. of Oncology", Kharkiv
Odessa regional clinical hospital Thoracic Surgery Department Academician Zabolotnoho, Odesa
Prykarpatskiy Regional Oncological Center, Ivano-Frankivsk
Liaoning Cancer Hospital & Institute, Shenyang
China-Japan Union Hospital of Jilin University Tumor department of Hematology, Changchun
Harbin Medical University Cancer Hospital, Harbin
Fourth Hospital of Hebei Medical University Breast cancer department, Shijiazhuang
Cancer Center of Guangzhou Medical University Breast Oncology, Guangzhou
Lead Sponsor
BeyondSpring Pharmaceuticals Inc.
INDUSTRY