T-piece Versus Pressure-support for the Spontaneous Breathing Trial

NACompletedINTERVENTIONAL
Enrollment

1,000

Participants

Timeline

Start Date

January 31, 2020

Primary Completion Date

June 7, 2021

Study Completion Date

September 7, 2021

Conditions
Weaning From Mechanical VentilationExtubation
Interventions
PROCEDURE

T-piece trial

T-piece trial will be performed for around 1 hour with a T-piece connected to the extremity of the endotracheal tube by simply disconnecting the patient from the ventilator and by providing additional oxygen (≤ 6 L/min)

PROCEDURE

Pressure-support trial

Pressure-Support trial will be performed for around 1 hour without disconnecting the patient from the ventilator, by using a low level of pressure-support (PS 8 cm H2O) with a FiO2 ≤ 40% and without positive end-expiratory pressure (PEEP), while continuously monitoring the respiratory rate and tidal volume on the ventilator display.

Trial Locations (1)

86000

Intensive reanimation, Poitiers

All Listed Sponsors
lead

Poitiers University Hospital

OTHER

NCT04227639 - T-piece Versus Pressure-support for the Spontaneous Breathing Trial | Biotech Hunter | Biotech Hunter