Treatment of Chronic Central Serous Chorioretinopathy Via Electromagnetic Stimulation and Platelet- Rich Plasma

NACompletedINTERVENTIONAL
Enrollment

22

Participants

Timeline

Start Date

December 1, 2018

Primary Completion Date

September 30, 2019

Study Completion Date

January 1, 2020

Conditions
Central Serous ChorioretinopathyChronic Central Serous Chorioretinopathy
Interventions
COMBINATION_PRODUCT

Source of growth factors: autologous platelet-rich plasma (aPRP) + repetitive electromagnetic stimulation for iontophoresis

"Autologous platelet rich plasma is containing many types of growth factors (GFs) such as epithelial growth factor (EGF), fibroblast growth factor (FGF), transforming growth factor (TGF), nerve growth factor (NGF), platelet-derived growth factor (PDGF), and insulin-like growth factor (IGF).~Repetitive high frequency electromagnetic stimulation (rEMS) creates a stimulated focus in the tissue by increasing blood flow and platelets at the capillary level. Electromagnetic stimulation along with growth factors has shown synergetic effects toward enhanced epithelial integrity and neural functions. With the addition of possible iontophoresis effects in the rEMS, the passage of the various active molecules can be augmented at the tissue level thereby increasing the widespread effect of the GFs in the damaged choroidal and outer retinal microenvironment."

Trial Locations (1)

06312

Ankara University Biotechnology Institute, Ankara

All Listed Sponsors
lead

Ankara Universitesi Teknokent

OTHER

NCT04224831 - Treatment of Chronic Central Serous Chorioretinopathy Via Electromagnetic Stimulation and Platelet- Rich Plasma | Biotech Hunter | Biotech Hunter