NeuroCognition After Carotid Recanalization

PHASE2CompletedINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

May 1, 2020

Primary Completion Date

March 14, 2024

Study Completion Date

March 14, 2024

Conditions
Cognition DisorderStrokeOcclusion Carotid
Interventions
PROCEDURE

Endovascular intervention

Endovascular angioplasty of the occluded carotid using balloon angioplasty and reconstruction with stents: coronary stents distally (Rebel, Boston Scientific; Vision, Abbott Vascular) and carotid stents proximal (Acculink and Xcat, Abbott Vascular) Patients will stay on their aspirin 325 mg and clopidogrel 75 mg

DRUG

Aspirin and Clopidogrel (maximal medical Therapy)

Best Medical Management: daily dual antiplatelet therapy (aspirin: 325 mg p.o. qd and Clopidogrel: 75 mg p.o. qd), optimization of systolic blood pressure (120 -140 mmHg), and smoking cessation.

Trial Locations (2)

27710

Duke University, Durham

52242

University of Iowa hospitals and Clinics, Iowa City

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Duke University

OTHER