NCT04218240View on ClinicalTrials.gov

Combining Pregabalin (LYRICA®) With Lofexidine (LUCEMYRATM) to Treat OPIOID Withdrawal

PHASE2CompletedINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

December 17, 2020

Primary Completion Date

August 31, 2023

Study Completion Date

August 31, 2023

Conditions
Opioid Withdrawal
Interventions
DRUG

Pregabalin 200 MG capsules

oral pregabalin 200 mg capsules given with a taper on day 5

DRUG

Placebo oral tablet

oral Placebo

DRUG

Lofexidine 0.18Mg Tab

lofexidine 0.18 tab given with a taper starting on day 5

Trial Locations (3)

10019

John Mariani, New York

19104

Treatment Research Center, Philadelphia

21229

Mountain Manor Treatment Center, Baltimore

All Listed Sponsors
lead

University of Pennsylvania

OTHER

NCT04218240 - Combining Pregabalin (LYRICA®) With Lofexidine (LUCEMYRATM) to Treat OPIOID Withdrawal | Biotech Hunter | Biotech Hunter