Effect of CPAP on 6-Minute Walk Test Outcomes in Patients With ECAC

NARecruitingINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

March 1, 2023

Primary Completion Date

January 31, 2026

Study Completion Date

January 31, 2026

Conditions
TracheobronchomalaciaExcessive Dynamic Airway Collapse
Interventions
DEVICE

Continuous positive airway pressure (CPAP) device

Use of a CPAP during a 6 minute walk test to maintain the airways open during the respiratory cycle

DEVICE

Sham-continuous positive airway pressure (CPAP) device

An enlarged air leak incorporated into the exhalation valve will be positioned between the mask and the CPAP tubing, allowing airflow resistance of the exhalation port to be almost eliminated by increasing its area, thereby virtually cancelling positive pressure. Also an orifice restrictor in the CPAP circuit will be connected between the CPAP unit and the tubing in order to load the blower with the same airflow resistance as in true CPAP.

Trial Locations (1)

02215

RECRUITING

Beth Israel Deaconess Medical Center, Boston

All Listed Sponsors
lead

Beth Israel Deaconess Medical Center

OTHER