NCT04216953View on ClinicalTrials.gov

MEK Inhibitor and a PDL1 Inhibitor Patients With Locally Advanced and/or Metastatic Soft Tissue Sarcoma

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

320

Participants

Timeline

Start Date

February 12, 2020

Primary Completion Date

February 1, 2026

Study Completion Date

February 1, 2027

Conditions
Sarcoma,Soft Tissue
Interventions
DRUG

Cobimetinib

"Adults: 20mg film coated tablet~Paediatrics:~i) powder for oral suspension containing 250mg of cobimetinib~ii) for pediatric patients ≥12 years-old and with a BW ≥60kg : 20mg film coated tablet same as adults"

DRUG

Atezolizumab

20-mL glass vial containing 1200 mg of atezolizumab.

Trial Locations (6)

13385

Hôpital de la Timone, Marseille

49055

Institut de Cancérologie de l'Ouest, Angers

59020

Centre Oscar Lambret, Lille

69008

Centre Léon Bérard, Lyon

94800

Institut Gustave Roussy, Villejuif

Unknown

Institut Curie, Paris

All Listed Sponsors
lead

Centre Leon Berard

OTHER