Association Between SNP of SP-D and Susceptibility and Prognosis of Infectious Keratitis

CompletedOBSERVATIONAL
Enrollment

145

Participants

Timeline

Start Date

October 1, 2016

Primary Completion Date

June 30, 2018

Study Completion Date

June 30, 2019

Conditions
Infectious Keratitis
Interventions
DRUG

Treatment of bacterial keratitis

0.3% Levofloxacin Eye Drops or 0.3% Tobramycin Eye Drops QID

DRUG

Treatment of fungal keratitis

1% Fluconazole Eye Drops or 0.25% Amphotericin B Eye Drops QID

DRUG

Treatment of viral keratitis

0.1% Acyclovir eye drops QID ,Ganciclovir gel QN,Famiclovir tablets 0.25g TID

DIAGNOSTIC_TEST

corneal scraping

culture and sensitivity of corneal ulcerated infiltrating edge tissue

OTHER

Sequencing

polymerase chain reaction with sequence specific primers(PCR-SSP) and Sanger sequencing

Trial Locations (1)

310000

Department of Ophthalmology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou

All Listed Sponsors
lead

Second Affiliated Hospital, School of Medicine, Zhejiang University

OTHER

NCT04213313 - Association Between SNP of SP-D and Susceptibility and Prognosis of Infectious Keratitis | Biotech Hunter | Biotech Hunter