Safety, Tolerability and Pharmacokinetics of HSK21542 in Healthy Volunteers

PHASE1CompletedINTERVENTIONAL
Enrollment

66

Participants

Timeline

Start Date

January 9, 2020

Primary Completion Date

September 6, 2020

Study Completion Date

December 7, 2020

Conditions
Healthy Volunteers
Interventions
DRUG

HSK21542

Intravenous injection 0.2 μg/kg solution (active or placebo, 0.5-1h after standard meal). Complete infusion within 15 min.

DRUG

HSK21542

Intravenous injection 0.5 μg/kg solution (active or placebo, 0.5-1h after standard meal). Complete infusion within 15 min.

DRUG

HSK21542

Intravenous injection 1 μg/kg solution (active or placebo, 0.5-1h after standard meal). Complete infusion within 15 min.

DRUG

HSK21542

Intravenous injection 1 μg/kg solution (active or placebo, 0.5-1h after standard meal). Complete infusion within 2 min.

DRUG

HSK21542

Intravenous injection 0.75 μg/kg solution (active or placebo, 0.5-1h after standard meal). Complete infusion within 15 min.

DRUG

HSK21542

Intravenous injection 1.5 μg/kg solution (active or placebo, 0.5-1h after standard meal). Complete infusion within 15 min.

DRUG

HSK21542

Intravenous injection 2.25 μg/kg solution (active or placebo, 0.5-1h after standard meal). Complete infusion within 15 min.

DRUG

HSK21542

Intravenous injection 3.375 μg/kg solution (active or placebo, 0.5-1h after standard meal). Complete infusion within 15 min.

DRUG

HSK21542

Intravenous injection 0.2 μg/kg solution (active or placebo, 0.5-1h after standard meal). Complete infusion within 2 min.

Trial Locations (1)

Unknown

Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou

All Listed Sponsors
collaborator

Second Affiliated Hospital, School of Medicine, Zhejiang University

OTHER

lead

Sichuan Haisco Pharmaceutical Group Co., Ltd

INDUSTRY

NCT04213196 - Safety, Tolerability and Pharmacokinetics of HSK21542 in Healthy Volunteers | Biotech Hunter | Biotech Hunter