NCT04208776View on ClinicalTrials.gov

Efficacy of Combination of Midodrine With Propranolol in Preventing First Bleed in Decompensated Cirrhotics With Severe Ascites.

NACompletedINTERVENTIONAL

Enrollment

140

Participants

Timeline

Start Date

February 4, 2020

Primary Completion Date

December 31, 2021

Study Completion Date

December 31, 2021

Conditions

Decompensated CirrhosisSevere Ascites

Interventions

DRUG

Propranolol

maximum tolerated dose of propranolol with initial dosage of 20mg once a day and uptitrating every 2nd day by 20 mg.

DRUG

Midodrine

It will be started at 2.5mg TDS and will be uptitrated every 2nd day to a max of 10mg TDS to attain a MAP of atleast 70mm Hg and then uptitate the beta blocker simulataneously to attain the target heart rate

Trial Locations (1)

110070

Institute of Liver and Biliary Sciences, New Delhi

All Listed Sponsors

lead

Institute of Liver and Biliary Sciences, India

OTHER

NCT04208776 - Efficacy of Combination of Midodrine With Propranolol in Preventing First Bleed in Decompensated Cirrhotics With Severe Ascites. | Biotech Hunter | Biotech Hunter