105
Participants
Start Date
March 25, 2020
Primary Completion Date
December 15, 2023
Study Completion Date
December 15, 2023
TJ011133
This is an open-label Phase 1/2a clinical study. The study will be conducted in two parts: Part I: Phase 1 dose escalation, TJ011133 is tentatively scheduled to be administered once weekly in 28-day treatment cycles;Part II: Phase 2a study TJ011133 will be administered at a dose of 30 mg/kg once weekly, and AZA will be administered at a dose of 75 mg/m2 by subcutaneous injection for 7 consecutive days from D1 to D7 in 28-day treatment cycles.
Peking Union Medical College Hospital, Beijing
Peking University International Hospital, Beijing
The First Hospital of China Medical University, Shenyang
The First Hospital of Jilin University, Changchun
Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai
Shanghai Sixth People's Hospital, Shanghai
Jiangsu Province Hospital, Suzhou
Qilu Hospital of Shandong University, Jinan
Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical, Tianjin
Tianjin Medical University General Hospital, Tianjin
The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou
The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou
The First Affiliated Hospital of Xiamen University, Xiamen
The First Affiliated Hospital of Chongqing Medical University, Chongqing
Union Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology, Wuhan
Henan Cancer Hospital, Zhengzhou
Guangdong Provincial People's Hospital, Guangzhou
Zhujiang Hospital Of Southern Medical University, Guangzhou
Nanfang Hospital, Guangzhou
Shenzhen Second People's Hospital, Shenzhen
The Affiliated Hospital of Guizhou Medical University, Guiyang
The second Affiliated Hospital of Kunming Medical University, Kunming
The Second Affiliated Hospital of Xi'an Jiaotong University(Xibei Hospital), Xi’an
Beijing Boren Hospital, Beijing
Sun Yat-sen University Cancer Center, Guangzhou
The Second Hospital of HeBei Medical University, Shijiazhuang
TJ Biopharma Co., Ltd.
INDUSTRY