Effect of Giving Reduced Fluid in Children After Trauma

NARecruitingINTERVENTIONAL
Enrollment

250

Participants

Timeline

Start Date

August 27, 2018

Primary Completion Date

August 31, 2026

Study Completion Date

September 30, 2026

Conditions
Critical IllnessPediatricsGeneral SurgeryFluid TherapyWounds and Injuries
Interventions
OTHER

Balanced crystalloid solution volume administration

Maintenance and bolus fluid volumes of balanced isotonic crystalloid solution administered based on arm.

OTHER

Packed Erythrocytes Units, Blood Product Unit volume

For patients designated as Bleeding, where hemoglobin \<7 then patient will be transfused 10 mL/kg up to 250 mL/transfusion. If patient is hypovolemic with clinician discretion transfuse 20 mL/kg.

OTHER

Plasma volume

For patients designated as Bleeding, where International Normalized Ratio (INR) \> 1.5 then patient will be transfused 10 mL/kg up to 250 mL/transfusion. If patient is hypovolemic with clinician discretion transfuse 20 mL/kg.

OTHER

Platelets volume

For patients designated as Bleeding, where platelets \< 50,000 then patient will be transfused 10 mL/kg up to 250 mL/transfusion. If patient is hypovolemic with clinician discretion transfuse 20 mL/kg.

Trial Locations (4)

10032

RECRUITING

Columbia University Irving Medical Center NewYork-Presbyterian Morgan Stanley Children's Hospital, New York

14203

NOT_YET_RECRUITING

John R. Oishei Children's Hospital of Buffalo, Buffalo

14642

RECRUITING

University of Rochester, Golisano Children's Hospital, Rochester

38103

RECRUITING

Le Bonheur Children's Hospital, Memphis

Sponsors
All Listed Sponsors
collaborator

Northwell Health

OTHER

collaborator

Johns Hopkins University

OTHER

collaborator

Cornell University

OTHER

collaborator

Childress Institute for Pediatric Trauma

UNKNOWN

lead

Columbia University

OTHER