250
Participants
Start Date
August 27, 2018
Primary Completion Date
August 31, 2026
Study Completion Date
September 30, 2026
Balanced crystalloid solution volume administration
Maintenance and bolus fluid volumes of balanced isotonic crystalloid solution administered based on arm.
Packed Erythrocytes Units, Blood Product Unit volume
For patients designated as Bleeding, where hemoglobin \<7 then patient will be transfused 10 mL/kg up to 250 mL/transfusion. If patient is hypovolemic with clinician discretion transfuse 20 mL/kg.
Plasma volume
For patients designated as Bleeding, where International Normalized Ratio (INR) \> 1.5 then patient will be transfused 10 mL/kg up to 250 mL/transfusion. If patient is hypovolemic with clinician discretion transfuse 20 mL/kg.
Platelets volume
For patients designated as Bleeding, where platelets \< 50,000 then patient will be transfused 10 mL/kg up to 250 mL/transfusion. If patient is hypovolemic with clinician discretion transfuse 20 mL/kg.
RECRUITING
Columbia University Irving Medical Center NewYork-Presbyterian Morgan Stanley Children's Hospital, New York
NOT_YET_RECRUITING
John R. Oishei Children's Hospital of Buffalo, Buffalo
RECRUITING
University of Rochester, Golisano Children's Hospital, Rochester
RECRUITING
Le Bonheur Children's Hospital, Memphis
Collaborators (2)
Northwell Health
OTHER
Johns Hopkins University
OTHER
Cornell University
OTHER
Childress Institute for Pediatric Trauma
UNKNOWN
Columbia University
OTHER