51
Participants
Start Date
March 10, 2021
Primary Completion Date
June 10, 2022
Study Completion Date
June 10, 2022
Patient group
Patients with Cushing Disease (CD) receiving a medical treatment: n = 30 Plasmatic cortisol UFC Urine biocollection Salive biocollection
Remission control group
Patients in remission of CD and having recovered a normal pituitary function for at least 12 months following pituitary surgery (normal UFC associated to: cortisol suppression following dexamethasone suppression test, or normal LNSC, or midnight serum cortisol \< 200 nmol/L) n = 15 Plasmatic cortisol UFC Urine biocollection Salive biocollection Haircortisol
Bilateral surrenalectomy control group
Patients with previous CD, treated with bilateral adrenalectomy and receiving weight adjusted doses of hydrocortisone for at least 6 months. Last daily dose of Hydrocortisone should be administered no later than 5 pm. n = 15 Plasmatic cortisol UFC Urine biocollection Salive biocollection Haircortisol
Service d'Endocrinologie, Diabète et Maladies Métaboliques - APHM, Marseille
Service d'Endocrinologie - CHU Caen, Caen
Service d'endocirnologie, diabète, nutrition, Hôpital Haut Lévêque - CHU de Bordeaux, Pessac
CIC d'Endocrinologie, Maladies Métaboliques et Nutrition - CHU de Nantes, Nantes
Service d'endocrinologie - HCL, Lyon
Service d'Endocrinologie - APHP Cochin, Paris
Service d'Endocrinologie et des Maladies de la Reproduction - APHP Bicêtre, Paris
University Hospital, Bordeaux
OTHER