Pulsed Field Ablation to Irreversibly Electroporate Tissue and Treat AF

NACompletedINTERVENTIONAL
Enrollment

421

Participants

Timeline

Start Date

December 10, 2019

Primary Completion Date

November 28, 2022

Study Completion Date

November 28, 2022

Conditions
Atrial Fibrillation
Interventions
DEVICE

Medtronic PulseSelect Pulsed Field Ablation (PFA) System

Adult subjects with a history of drug refractory recurrent symptomatic atrial fibrillation (AF) will undergo ablation of pulmonary veins and confirmation of entrance block and, where assessable, exit block with the PulseSelect PFA System.

Trial Locations (41)

4010

Ordensklinikum Linz GmbH / Elisabethinen, Linz

8000

AZ Sint-Jan Brugge-Oostende av, Bruges

10016

NYU Langone Health - Heart Rhythm Center, New York

10467

Montefiore Medical Center, The Bronx

11030

Northwell Health - North Shore University Hospital, Manhasset

15213

University of Pittsburgh Medical Center- UPMC Presbyterian, Pittsburgh

18901

Doylestown Hospital, Doylestown

19104

Hospital of the University of Pennsylvania, Philadelphia

20010

MedStar Washington Hospital Center, Washington D.C.

21287

The Johns Hopkins Hospital, Baltimore

22908

University of Virginia Medical Center, Charlottesville

28007

Hospital General Universitario Gregorio Marañón, Madrid

28803

Mission Hospital, Asheville

30322

Emory Saint Joseph's Hospital, Atlanta

33607

BayCare Saint Joseph's Hospital, Tampa

35243

Grandview Medical Center, Birmingham

43210

The Ohio State University Wexner Medical Center, Columbus

44195

Cleveland Clinic, Cleveland

48073

Beaumont Hospital, Royal Oak

49503

Spectrum Health, Grand Rapids

50314

Iowa Heart Center, Des Moines

55902

Mayo Clinic (Rochester MN), Rochester

60611

Northwestern University Hospital, Chicago

64111

Saint Luke's Mid America Heart Institute, Kansas City

78705

St. David's Medical Center, Austin

80538

Medical Center of the Rockies, Loveland

92200

CMC - Clinique Ambroise Paré, Neuilly-sur-Seine

97225

Providence Saint Vincent Medical Center, Portland

98122

Swedish Medical Center Cherry Hill, Seattle

02720

Southcoast Health System, Fall River

07450

The Valley Hospital, Ridgewood

Unknown

John Hunter Hospital, New Lambton Heights

Southlake Regional Health Centre, Newmarket

V5Z1M9

Vancouver General Hospital, Vancouver

H3G1A4

McGill University Health Centre, Montreal

G1V4G5

Institut Universitaire de Cardiologie et de Pneumologie de Québec (IUCPQ), Québec

036-8563

Hirosaki University Hospital, Hirosaki

910-1193

University of Fukui Hospital, Yoshida-gun

113-8519

Tokyo Medical and Dental University, Medical Hospital, Bunkyō-Ku

105-8471

Jikei University, Minato-Ku

3435 CM

St. Antonius Ziekenhuis, Nieuwegein

All Listed Sponsors
lead

Medtronic Cardiac Ablation Solutions

INDUSTRY

NCT04198701 - Pulsed Field Ablation to Irreversibly Electroporate Tissue and Treat AF | Biotech Hunter | Biotech Hunter