NCT04196413 - GD2 CAR T Cells in Diffuse Intrinsic Pontine Gliomas(DIPG) & Spinal Diffuse Midline Glioma(DMG) | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

June 4, 2020

Primary Completion Date

July 31, 2028

Study Completion Date

July 31, 2043

Conditions

Glioma of Spinal CordGlioma of Brainstem

Interventions

DRUG

GD2 CAR T cells

Autologous T-Cells transduced with retroviral vector (14g2a-CD8.BB.z.iCasp9) expressing GD2-chimeric antigen receptor

DRUG

Fludarabine

Fludarabine 25 mg/m2 per day IV for days -4, -3, -2

DRUG

Cyclophosphamide

Cyclophosphamide 500 mg/m2 per day IV for days -4, -3, -2

Trial Locations (1)

RECRUITING

Lucile Packard Children's Hospital (LPCH), Stanford