B-Enhancement of HBV Vaccination in Persons Living With HIV (BEe-HIVe): Evaluation of HEPLISAV-B

PHASE3CompletedINTERVENTIONAL
Enrollment

638

Participants

Timeline

Start Date

December 14, 2020

Primary Completion Date

August 13, 2024

Study Completion Date

August 13, 2024

Conditions
HIV InfectionHepatitis B
Interventions
BIOLOGICAL

HEPLISAV-B

Administered by IM injection

BIOLOGICAL

ENGERIX-B

Administered by IM injection

Trial Locations (41)

1862

Soweto ACTG CRS, Johannesburg

2092

Wits Helen Joseph Hospital CRS (Wits HJH CRS), Perth Road, Westdene, Johannesburg

4052

Durban International Clinical Research Site CRS, Durban

4118

De La Salle Health Science Institute Angelo King Medical Research Center, Silang

10000

Hanoi Medical University CRS, Đống Đa

10005

Joint Clinical Research Centre (JCRC)/Kampala Clinical Research Site, Kampala

10010

Weill Cornell Chelsea CRS, New York

10032

Columbia P&S CRS, New York

10065

Weill Cornell Uptown CRS, New York

10330

Thai Red Cross AIDS Research Centre (TRC-ARC) CRS, Bangkok

14642

University of Rochester Adult HIV Therapeutic Strategies Network CRS, Rochester

15213

University of Pittsburgh CRS, Pittsburgh

19104

Penn Therapeutics CRS, Philadelphia

20005

Whitman-Walker Health CRS, Washington D.C.

20200

Kenya Medical Research Institute/Walter Reed Project Clinical Research Center (KEMRI/WRP) CRS, Kericho

21287

Johns Hopkins University CRS, Baltimore

27401

Greensboro CRS, Greensboro

27599

Chapel Hill CRS, Chapel Hill

35222

Alabama CRS, Birmingham

43210

Ohio State University CRS, Columbus

44106

Case Clinical Research Site, Cleveland

45219

Cincinnati Clinical Research Site, Cincinnati

47183

Vanderbilt Therapeutics (VT) CRS, Nashville

50200

Chiang Mai University HIV Treatment (CMU HIV Treatment) CRS, Chiang Mai

60611

Northwestern University CRS, Chicago

77009

Houston AIDS Research Team CRS, Houston

80045

University of Colorado Hospital CRS, Aurora

90502

Harbor-UCLA CRS, Torrance

91350

Hospital Nossa Senhora da Conceicao CRS, Porto Alegre

92103

UCSD Antiviral Research Center, San Diego

94110

Ucsf Hiv/Aids Crs, San Francisco

90035-4709

UCLA CARE Center CRS, Los Angeles

30308-2012

The Ponce de Leon Center CRS, Atlanta

02114

Massachusetts General Hospital CRS (MGH CRS), Boston

02115

Brigham and Women's Hospital Therapeutics Clinical Research Site (BWH TCRS) CRS, Boston

63110-1010

Washington University Therapeutics (WT) CRS, St Louis

07103

New Jersey Medical School Clinical Research Center CRS, Newark

98104-9929

University of Washington AIDS CRS, Seattle

Unknown

Gaborone CRS, Gaborone

Blantyre CRS, Blantyre

21040-360

Instituto de Pesquisa Clinica Evandro Chagas (IPEC) CRS, Rio de Janeiro

Sponsors
All Listed Sponsors
collaborator

Dynavax Technologies Corporation

INDUSTRY

lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT04193189 - B-Enhancement of HBV Vaccination in Persons Living With HIV (BEe-HIVe): Evaluation of HEPLISAV-B | Biotech Hunter | Biotech Hunter